Smart drugs haven’t disappeared from Polish market and from young people’s live despite of becoming illegal in 2010. Today, the Internet offers to the teenagers at east eight Polish-language e-shops with cheap handling and shipping to Poland. Composition of the smart drugs is not fully recognized, because is constant changing. In offer we can find it as drought plants (such as Spice), tablets (party pills), powders. It is selling as a collectibles, not for human consumption. Smart drugs include both synthetic chemicals and powdered seeds or drought plants known as a strong psychostimulants or hallucinogens. It imitates the effect of taking popular drugs as marijuana, opium, amphetamine or ecstasy. Like other psychostimulants can cause addiction with long-term use, or can leads to experiment with “hard drugs”. In addition to stimulating, relaxing, hallucinogenic activities, smart drugs cause many side effects from both groups of mental and serious somatic disorders, can leads to serious disturbances of consciousness, arrhythmias or respiratory distress. The clinical diagnosis is based on clinical symptoms and information of the unknown substance ingestion. Due to the lack of specific antidotes, the treatment is only symptomatic and supportive virtual functions. The psychological or psychiatric consultation is often needed.