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Melkersson–Rosenthal syndrome in a child – a rare diagnostic challenge. Case report

Natalia Gołuchowska1, Aldona Ząber1, Agata Będzichowska1, Jakub Jagiełło2, Karolina Agnieszka Iwanicka3, Bolesław Kalicki1,4, Agnieszka Rustecka1

Affiliation and address for correspondence
Pediatr Med Rodz 2026; 22 (2): 114–118
DOI: 10.15557/PiMR.2026.0018
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Abstract

Facial nerve palsy has a heterogeneous aetiology. One of the rare causes of recurrent seventh cranial nerve palsy is Melkersson–Rosenthal syndrome, which is diagnosed primarily on the basis of its characteristic clinical presentation. This paper presents the case of a 17-year-old female patient hospitalised with right-sided peripheral facial nerve palsy. Physical examination, in addition to features of seventh cranial nerve palsy, revealed characteristic fissuring of the tongue. The medical history further indicated a previous episode of contralateral facial nerve palsy and recurrent self-limiting episodes of facial oedema. Extended laboratory and imaging diagnostics excluded infectious, neoplastic, autoimmune, and traumatic aetiologies. Based on the fulfilment of the diagnostic criteria, Melkersson–Rosenthal syndrome was diagnosed. Systemic glucocorticosteroid therapy, supportive treatment, and intensive rehabilitation were initiated, resulting in partial improvement in neurological status.

Keywords
facial nerve paralysis, Melkersson–Rosenthal syndrome, facial nerve paralysis in children, Melkersson–Rosenthal syndrome treatment

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