LOGO
PL

Heart failure as a multi-system clinical syndrome – an experience in cohort of acutely decompensated patients

Agata Galas, Paweł Krzesiński, Grzegorz Gielerak, Wiesław Piechota, Beata Uziębło-Życzkowska, Adam Stańczyk, Katarzyna Piotrowicz, Agnieszka Jurek, Łukasz Michalczyk, Małgorzata Kurpaska, Małgorzata Banak, Andrzej Skrobowski
Affiliation and address for correspondence
Pediatr Med Rodz 2019, 15 (2), p. 137–144
DOI: 10.15557/PiMR.2019.0024
PlumX metrics:
Abstract

Background: Heart failure is a condition with diverse aetiology and pathogenesis. This is associated with higher rates of comorbidities, such as i.e. hypertension, atrial fibrillation chronic kidney disease, anaemia and iron deficiency. The purpose of this study was to characterise patients hospitalised due to acutely decompensated heart failure, with a particular emphasis on any comorbidities and laboratory test abnormalities. Material and methods: A total of 102 patients aged over 18 years, hospitalised due to acute decompensated heart failure. Thorough medical history (including any concomitant diseases) was obtained from all patients. They also underwent a clinical examination and biochemical tests. Results: The subjects included were mostly men (76.5%) with ischemic aetiology (63.7%). The most common comorbidity was hypertension (66.6%), while hypotension affected only 2% of patients. The most common heart failure subtype was heart failure with reduced ejection fraction (60.8%). The detected blood test abnormalities included elevated cystatin C levels in 94.7%, hyperuricaemia in 75.5%, anaemia in 55.9%, and iron deficiency in 78.3% of patients. Conclusion: Most of acute decompensated heart failure patients suffer from comorbidities with a documented impact on prognosis. Cardiovascular decompensation poses a risk of multi-organ dysfunction and estimating its actual consequences requires a detailed assessment of complex laboratory tests, including levels of creatinine, cystatin C, uric acid, red blood cell parameters and iron metabolism parameters.

Keywords
acute heart failure, laboratory tests, kidney failure, creatinine, anaemia

Oświadczam, że posiadam prawo wykonywania zawodu lekarza i jestem uprawniony do otrzymywania specjalistycznych informacji medycznych. Chcę zapoznać się z informacją z serwisu.