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Acute pancreatitis as an initial manifestation of primary hyperparathyroidism: a case report

Karolina Agnieszka Iwanicka1, Jakub Jagiełło2, Laura Maria Surdacka-Barańska3, Mateusz Kaczmarski4, Adam Daniel Durma5,6, Marek Saracyn5,6, Grzegorz Wiktor Kamiński6

Affiliation and address for correspondence
Pediatr Med Rodz 2026; 22 (3)
10.15557/PiMR.2025.0028
Abstract

Acute pancreatitis is one of the most common gastroenterological diseases. The diagnosis of acute pancreatitis requires the presence of at least two of the following criteria: a typical clinical presentation, serum lipase and/or amylase levels exceeding three times the upper limit of normal, or imaging studies characteristic of acute pancreatitis. Numerous conditions may contribute to the development of acute pancreatitis, the most common being chronic alcohol abuse and cholelithiasis (gallstones). Rare causes of acute pancreatitis include, among others, hypercalcaemia. This article presents the case of a woman with recurrent episodes of acute pancreatitis caused by hypercalcaemia (peak serum calcium level: 13.3 mg/dL; peak serum parathyroid hormone level: 416 pg/mL), who was ultimately diagnosed with a parathyroid adenoma. The diagnostic workup and treatment are also described. Appropriate management of patients with acute pancreatitis requires an understanding of the disease aetiology.

Keywords
acute pancreatitis, hypercalcaemia, hyperparathyroidism

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